Bob Dylan's Ramona came out in 1965 -- here Dylan sings it in Manchester. According to a comment on songmeanings.com, Ramona was a name he used in letters to Joan Baez.
In the song, he says "There's no one to beat you, no one to defeat you, 'cept the thoughts of yourself feeling bad."
He tells Ramona her sorrow stems from "forces and friends that hype you and type you, making you feel that you must be exactly like them."
The bard says he "cannot explain that in lines."
Yet many have related to these lyrics and many have sung this song. Sinead Lohan for one.